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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MED13 All Species: 33.33
Human Site: S2022 Identified Species: 61.11
UniProt: Q9UHV7 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UHV7 NP_005112.2 2174 239318 S2022 L P A S P T G S P V H S P G S
Chimpanzee Pan troglodytes XP_001138050 2188 240763 S2036 L P A S P T G S P V H S P G S
Rhesus Macaque Macaca mulatta XP_001110128 2174 239364 S2022 L P A S P T G S P V H S P G S
Dog Lupus familis XP_537704 2182 240593 S2030 L P A S P T G S P V H S P G S
Cat Felis silvestris
Mouse Mus musculus Q5SWW4 2171 238573 S2019 L P A S P T A S P V H S P G S
Rat Rattus norvegicus NP_001100505 2040 223488 S1892 P T T S P V H S P G S H Y P H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509907 2170 238695 S2018 L P A S P T G S P V H S P G S
Chicken Gallus gallus XP_415884 2225 244861 S2073 L P A S P T G S P V H S P G S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A2VCZ5 2102 230974 S1953 I P N S P T T S P V H S P G S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7KTX8 2618 280005 S2459 D T H M D R V S N H G S P G R
Honey Bee Apis mellifera XP_393643 1982 216109 H1834 G G S G L G N H D G P G S P F
Nematode Worm Caenorhab. elegans Q93442 2862 325119 A2712 L E T P S S A A I R Q T G G P
Sea Urchin Strong. purpuratus XP_001203054 1127 123639 A979 I P T D G G P A P A A Q G P G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.8 97.7 94.1 N.A. 92.5 87.8 N.A. 89.5 84.6 N.A. 64.8 N.A. 24.7 35 21 25.7
Protein Similarity: 100 98.3 98.4 96 N.A. 96.4 91.2 N.A. 94 90.5 N.A. 76.9 N.A. 41.3 51.5 37.4 36
P-Site Identity: 100 100 100 100 N.A. 93.3 26.6 N.A. 100 100 N.A. 80 N.A. 26.6 0 13.3 13.3
P-Site Similarity: 100 100 100 100 N.A. 93.3 26.6 N.A. 100 100 N.A. 86.6 N.A. 26.6 6.6 33.3 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 54 0 0 0 16 16 0 8 8 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 0 8 8 0 0 0 8 0 0 0 0 0 0 % D
% Glu: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % F
% Gly: 8 8 0 8 8 16 47 0 0 16 8 8 16 77 8 % G
% His: 0 0 8 0 0 0 8 8 0 8 62 8 0 0 8 % H
% Ile: 16 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 62 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 8 0 0 0 8 0 8 0 0 0 0 0 0 % N
% Pro: 8 70 0 8 70 0 8 0 77 0 8 0 70 24 8 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 8 8 0 0 0 % Q
% Arg: 0 0 0 0 0 8 0 0 0 8 0 0 0 0 8 % R
% Ser: 0 0 8 70 8 8 0 77 0 0 8 70 8 0 62 % S
% Thr: 0 16 24 0 0 62 8 0 0 0 0 8 0 0 0 % T
% Val: 0 0 0 0 0 8 8 0 0 62 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _